COX-SACK-IE V

COX-SACK-IE V:
A-->h
A ND, FOOT & MOUTH
A NGINA (HERP)
A SEPTIC MG

B-->
B ARRE-GUILAIN

COX-SACK-IE V

COX-SACK-IE V:
A-->h
A ND, FOOT & MOUTH
A NGINA (HERP)
A SEPTIC MG

MOUTH--> STR. MUTANS

MOUTH--> STR. MUTANS
+GLU--> LACTATE-->
\pH--> CARIES

GENETIC TRNSFER

GENETIC TRNSFER
transFROMation
DNA FROM OUT

trans
DUCKtion
DUCK=PHAGE+DNA

CONJUGATION
Hfr F+--> F-

TRANS-POS-ONS=
JUMPING GENES-->
RESISTANCE

Bacterial Toxins

SPECIFIC STRUCTURES
Gr+ TEICHOIC ACID
Gr- LPS-->LIPID A
N-DO-TOXIN
N EGATIVE Gr-
2 MEMBRANES-DD. Gr+

EX-OTOXINS
EX-CRETED= PEPTIDE

BACTERIAL FEEDING

BACTERIAL FEEDING
AUX OTROPH REQUIRE
AUX ILIARY NOURISHEMENTS

LAG-->LOG-->STAT>death

PSEUdomonas

PSEUdomonas
P NEUMONIA
S EPSIS--> BLACK LESIONS
E XTERNAL OTITIS
U TI

HEPATITIS VIRUSES

HEPATITIS VIRUSES:
A Sx
B LOOD-BORNE= 6H
Be WARE! HBeAg
C-->4
C HRONIC 50%
C ARRIERS
C IRRHOSIS
C A
D EFECTIVE
D EPENDENT ON HBV
E NTEROV
E PIDEMICS
E XPECTANT mothers=pregnant

HBV=6H
H EMO-PHILIACS
H EROIN USERS
H OMO-SEXUALS
H EALTH WORKERS
H OMES=PRISON-ERS
"H" =PROSTITUTES?

POLIO VACCINE

POLIO VACCINE:
SAL
K
K ILLED
SC--> NO IgA DD.
SABIN= LIVE OPV but SE VAPP

CLOSTRIDIA

CLOSTRIDIA:
T ETANUS
T ONE/
T RISMUS
T ENNIS RACKET
T OXOID--> TREATMENT
DD.
B OTULINUM
B OTTLE
B LOCK Ach RELEASE

P ERFRINGENS
P ERFORATES by
LE cithinase
LE thal

DI fficile
DI arrhea

Related mnemonic:

Mnemonic for Enterocolitis: "Vomit Big GREY Smelly Chunks"

DIPHTHERIA Dx= ABCDEFG

DIPHTHERIA Dx= ABCDEFG:
A DENOPATHY=LN/
BULLNECK
b PHAGEEXO-TOXIN
C HINESE LETTER
CRAM+
D YS-PHONIA
E LONGATION
F ACTOR2 EF2
RIBOSOMES
G RANULES-meta-chromatic

TOXIN 2 PARTS
B
B INDS MEMBRANE
A
A CTIVE

DT 10y PROTECTION

DTP~
PTE Sx:
D YS-PNEA SOB DDx=
CAPE
T ACHY-CARDIA
P AIN CHEST ~ MI

Mnemonic: Malaria

Malaria

Exo-erytrocytes = liver --> vivax 50% + ovale 1%, relapse, long life in erythrocytes

Malaria, no relapse = falciparum 45%

Falciparum 60% + "banana" = ring forms, knobs --> CNS coma

Mature W
Malariae 1%

Lolita
Vivax+Ovale
Signet ring + dots

Related reading:

New therapeutic strategy for malaria: overcome T cell exhaustion by blocking co-inhibitory receptors. Nature, 2012.

Viruses

PROTEIN SYNTHESIS
from
N---->C end
amiNo aCids
are tied from N to C

DNA VIRUSES-->
REPLICATION IN NUCLEUS
EXC. POX-VIRUS

RNA VIRUSES-->
REPLICATION IN CYTOPLASM
EXC. FLU

ANTIBIOTICS

ANTIBIOTICS-->
PROTEIN SYNTHESIS
INHIBITORS:
buy AT 30,
CELL at 50
A MINO-GLYCOSIDES
T ETRA-CYCLINES
Cl-AMPHENICOL
E RYTHRO-MYCN
L INCOMYCN
cL indamycin


TETR
A CYCLINE
A CCEPTOR SITE

CHLORAM
P HENICOL
P EPDIDYL SITE

amin
NOglycoside
N EPHROTOXICITY
O TOTOXICITY

ERY-
t ROMYCINE
t RNA -->NO RELEASE

AMPHO-
TERRIBLE SE
TEARS
HOLES IN MEMBRANE

STREPTOCOCCUS

STREPTOCOCCUS--->
HEMOLYSIS
• a PN-coccus
• b
GAbHS
B
• gamma= NO


AM / PM
gAbhs Pyogenes str.
M-protein=CAPSULE

RHEUMATIC FEVER=
PECCS:
P OLYA
E RYTHEMA MARGINAT. C HOREA MINOR
C ARDITIS
S UBCUT. NODULES

Bacteria: Gram Negative and Gram Positive

Gr- BACTERIA
NEISSERIA FERMENTATION:
G.-----> Glu ONLY
MG--->
Maltose + Glu

LACTASE+:
CEEK MILK
C ITROBACTER
E. COLI
E NTEROBACTER
K LEBSIELA


Gr+ ENZYMES:
STAPH. have more
STAFF > STREPTOC.---->
CATALASE+----> PMN
ST.AUREUS-
COAGULASE+
=LIMITS ABSCESS

Mnemonic for Enterocolitis: "Vomit Big GREY Smelly Chunks"

Mnemonic for Enterocolitis: "Vomit Big GREY Smelly Chunks"

Vomit - Vibrio cholerae
Big - B.cereus (reheated rice - "be cerious")

Giardia - G AS/
Rotavirus
Entamoeba
E. coli
Yersinia enterocolitidis

"Smelly"
Staph. aureus
Shigella

Campylobacter
Cryptosporidium
Clostridium - perfr., difficile, botulinum

ENTERO-BACTERIA

ENTERO-BACTERIA Ag= KOH
K APSULAR=poly-saccharide
O UTER MEMBRANE=2
sO MATIC=
LPS--->
L IPID A=
N -DOTOXIN
N EGATIVE Gr

H ELLICOPTER BLADE
FLAG H ELLAR= PROTEIN
CEEK ---> LACTOSE= glu-gal

MYCOSES

MYCOSES:
2 FORMS
• COLD SOIL
MOLDSPORE
• WARM body
• YEAST


B LASTO-MYCOSIS:
B IG B ROAD
B ASED
B UDDING YEAST
D.D. CRYPTO-COCC.
NO 2 FORMS:
ASPERGI-LLUS
HYPHAE 45o
MOLD FRUITING
BODY
CRYPTO-COCCUS
CRYPTO-GRAPHER
USES INDIA INK
YEAST ONLY
THE ONLY ONE+
CAPSULE

HISTO-PLASMA~ TB
TB ASPERGILLUS
COCCID.~BLASTOM.
CUP +NUTS
PARAC.~ CROWN
Or SHIPPING WHEEL

SPORO-
T RIX ON
T HORNS!
M UCOR
eM PTY

URINARY ANTI-SEPTICS

URINARY ANTI-SEPTICS:
N-FURANTOIN
NALIDIXRAPID
RESISTANCE ~ RMP
METHEN-AMINE FORMAL-ALDEHYD
PROTEUS- NO EFF.