VSD

VSD

Most commonly
Membranous portion of septum

VSD
Vegetations
Viridans strep in SABED

PDA

PDA
Pre-term infant
Pulmonary disease
Pulmonary obstructive vascular disease - Eisenmenger's
PA dilation
Prophylaxis for SABED
Pink arms - DDx blue legs
Persistent continuous murmur, like a machine

Ductus
Differential cyanosis

Up = pink
Down = blue

ASD

ASD

Split S2 (fixed)
Split R = RBBB in V1, rSR1

ASD II
Secundum 90%
Sky high in
Septum
Split S2
Second inter-space

RVH + heave
RBBB
Rr1
Relative PVS --> murmur
RT Infections

ASD I
Down in septum
Down syndrome

Tetralogy of Fallot

FALLOT-->PROVE it

P ULMONARY V. STENOSis
R VH
O VER-RIDING AORTA
V SD
E RYTHRO-POETIN increased to 70%, normal is 40%, leads to hyperviscosity

Marfan syndrome

Marfan syndrome symptoms: MARFAN

MVP
Ao aneurysm
Reduced vision
Fibrilin defect
Arachno-dactyly
N

FRAGILE X

FRAGILE X
M ALE
M ULTIPLE CGC REPEATS
M ENTAL RETARDATION
M ANDIBLE^
M ACRO-ORCHIDISM^

Henoch - Schönlein Purpura (HSP) Mnemonic: "10 P's"

HSP = 10 P's

PALPABLE
PURPURA
PLATELETS OK -- DDx from ITP
PRURITUS -- URTICARIA
PAIN -- ABDOMEN and LEGS
POSITIVE +guaiac -- FECES
PRESSURE -- increased blood pressure
PROTEINURIA
PREDNISONE = Tx

Related reading:

A Young Man with Henoch-Schönlein Purpura

Henoch-Schönlein Purpura - JAMA Patient Page http://goo.gl/e05qx

ERYTHROPOESIS cycle

ERYTHROPOESIS:
Young Liver Synthesizes Blood

Y OLK SAC
L IVER
S PLEEN
BMarrow

TWINS

TWINS
MONO ZYCOTIC
MONO CHORIONIC

DI ZYGOTIC
DI CHORIONIC

RUBELLA= 4T

RUBELLA= 4T
T ORCH
T OGA VIRUS
T EODOR Sx=/LN
T RIAD= GREGG

LUES 3~ OSTG.IMPERFCTA-->
ALL 3 = FACE PROBLEMS

INFANT DEPRIVATION Sx

INFANT DEPRIVATION Sx
R.Spitz= 4 W
W EAK= TONE\
W ORD\
W ANTING attention
W ARY predpazliv
+ANA-CLITIC DEPRESSION

SPHINGO-LIPID SYNTHESIS

SPHINGO-LIPID SYNTHESIS:
AA SERINE+
FFA PALMITATE=
SPINGO-SINE+
FFA--> CERAMIDE:

DISEASE--> GRAY MATTER ONLY-->
IN NEURONES

Gal STAYS-->FABRY
XR 50y
META-CHROMATIC
LEUCO-DYSTROPHY

NO-MAN
P ICKs
P HOSPHATE
his nose with
hiSPHINGer
SPHINGomyelin

+MONO-SACCARIDE
G lu-CEREBROSIDE
G AUSHER
G LUCO-CEREBRO-SIDase\

S STAYS--> KRABBE

+OLIGO-SACCHARIDE-->
GANGLIO-SIDE
TAY-
SA X
HE X OS-AMIN-IDASE A

NUCLEOTIDE SALVAGE

NUCLEOTIDE SALVAGE:
DNA, RNA-->
BREAKDOWN-->
BASES-->90% RE-UTILIZATION
~ BILE SALTS

SALVAGE:
BASE READY+ PRPP-->
NUCLEOTIDE
SAVES ENERGY

Lesch Lacks
Nyhan Nucleotide
Syndrome Salvage
\HGPRT-->
NO GMP PRODUCTION=
NO SYNTHESIS INHIBITION-->
PRPP*200-->SYNTHESIS/-->
GOUT

RADiation

RADiation
RAD
200-->20% DEATH
800-->100% DEATH
SENSITIVITY decrease
BM-->GONAD-->INTESTINES

POSONING

POSONING--> KIDS:
D RUGS C AN C AUSE P OISONING B UT I & L AVAGE C AN C OPE

D RUGS
C AN
C LEANERS
C AUSE
C OSMETICS
P OISONING
P LANTS
I
I PECAC
L AVAGE
C AN
C HARCOAL
C OPE
C ATHARCTICS

CHDislocation

CHDislocation
ORTHOLANI TEST
90* FLEX+
90* ABD=N

Aortic Coarctation

Co A
Co NTOUR= 3 Sx
Co MBINATN-->BI-CUSP.AV
Co LLATERAL ARTERIES->
C XR-->RIB NOTCHING
Co LD LEGS
C LAUDICATION
C HEST PAIN

2 TYPES:
aD ULT
D ISTAL to
D UCTUS

I NFANTILE
I NCLOSE to the HEART

CYANOTIC CHD: 5 T

CYANOTIC CHD = 5 T

T ETRALOGY of FALLOT
T GA --> BAS
T RUNCUS ART. communis --> DiGeorge
T RICUSPID ATRESIA
T APVReturn Connections +ASD

CXR=8,SNOW-MAN

4 PV
4 TYPES~ASD

FALLOT-->PROVE it
P ULMONARY V. STENOS
R VH
O VER-RIDING AORTA
V SD
E RYTHRO-POETIN/

WELL-CHILD Physical exam: WHALE FETCH

W t
H t
A BD
L UNGS
E XT RoM

F ONTANELLE
E YE+ EAR
T EST BABINSKI
C IRCUMFER HEAD
H EART

WELL BABY RoS: BE LAVISH

B IRTH Hx
E ATING HABITS

L ANGUAGE
A NY RECENT ILL-NESSES
V ISION
I MMUNIZATN
S LEEP. HABITS
H EAR-ING