Medical Mnemonics: Endocrinology

Showing posts with label Endocrinology. Show all posts

Luteinizing hormone (LH)

Luteinizing hormone (LH)

LH
Looks like hCG

Diabetes insipidus (DI)

Diabetes insipidus (DI)

PEPINO

Poly-uria
Excessive thirst
Poly-dypsia
Increased Na+
No H2O - dehydration
Osmolality - plasma increased, urine decreased - DDx SIADH

GIT HORMONES

GIT HORMONES:
FOOD-->
/G ASTRIN-->
/G ASTRIC Hcl-->
Zollinger-Ellison

CCK+SECRETIN->pancreas

FAT-->
C CK-->ENZYMES
C ONTRACTS GALLBLD

Hcl-->
/ S ECRETIN-->
/ S ECRETION HCO3-

APO-LPP~RECEPTORS
a
a--> SPEPhoresis
A CTIVATES LCAT
MOVES CHOL BACK IN
H DL
H EALTHY=NO APO b

b
b--> SPEP
B ED
B INDS--> LDL-RECEPTOR

C
C oFACTOR--> LPL

E
E XTRA UPTAKE OF REMNANTS

b--> ALL the REST
VL, I, L, -DL

DM - insulin and glucagon

AFTER MEAL:
4\ + 1/INSULIN-->
GLU AA FFA-->BUILD UP

FASTING/EXERCISE:
4/E GLUGON GH CS
+1\--> OUT

Cholesterol and gallstones

H DL--> NO APO B
H EALTHY

b
B ED--> the REST 3 LPP:
V, I, L DL

GALL-STONES=F
F AT
F ORTY
F EMALE

CHOLESTRL+MIXED=80%
PIGMENT 20%

C OMPLICATIONS
C HOLE-CYSTITIS
C HARCOT TRIAD
C OLIC= bmj F

bmj F:
b ILIARY COLIC
m URPHY Sx--> RUQ
j AUNDICE 20%
F EVER

S TONES GBL, PIGMENT
S PHERO-CYTOSIS
S PECTRIN
S ALINE TEST
o S MOTIC RESIST\
S PLEEN/ CHIME DDx
S EQUESTR-ATION
S MALLEST CAP.DIAMETR
S LUGGISH CIRCULATION
S TOPS RBC DESTRUCT
S URGICAL Tx
S WEDEN NORTH.EUR.
S HORTAGE LOSS
of MEMBRANE

DDx.
TARGET RBC
REDUNDANT MEMBRANE
DDx= HILLS

AD
DDx.
G6PD
M EDI-TERR-ENIANN
M ANY DRUGS
M ALARIA Tx
M ALE ONLY XR

ANTI-THYROID DRUGS

ANTI-THYROID DRUGS:
-THION-AMIDE S=C-N
\ORGANIFICTN<--C-MAZL P ER-OXIDASE\ P -S-URACIL\ P ERIPHERAL CONVERSION\ T4-->T3
P MN\ 0.1 %

-KI*30 NORM-->
\VASCUL. before SURGERY
TRANSIENTLY DD.

-131 I*--> PERMANENT
-bAR BLOCK= PROPRANL

DM

SKEW-->NAME AFTER
TAIL: - +
^---- IDDM +-->DKA
---^ NDDM -

MENO-PAUSE

MENO-PAUSE=
HAVOC:
H OT FLASH
A TROPHY-->
V AGINA
O STEO-POROSIS
C AD

Calcium Metabolsim Drug

Ca2 DRUGS:
1. Vit.D--> PO
-ERGO-
-TRIOL-->CRF
2.SAL-CATONIN SC
+ETI-DRONATE
\OSTEO=CLASTS
\BONE RESORPTION
\SERUM Ca2

CONTRA-CEPTIVES

CONTRA-CEPTIVES:
1.CoC
ESTROGEN-->FSH decrease
PROGESTERN--> LH decrease=
NO OVULATION
L H-->OVU
L ation

2.PoP NON STOP
MUCUS change ONLY-DD. 1

3. MORNING AFTER PILL=
ESTROGEN ONLY
4.IMPLANT NOR-GESTREL~
PROGESTERON--> 5y!

ENDOMETRIAL&OVARIAN CA decrease

GONADAL DRUGS

GONADAL DRUGS:
1. GnRH AGONIST=
LEUPROLIDE
GONADO-RELIN
-PULSE--> /FSH & LH
-CONTINUOUS-->FSH&LH decrease--> PROSTATIC CA

2.CLOMI-PHEN=
REMOVES ESTROGEN
FEED-BACK--> /FSH&LH-->
SO used in IVF

3. DANAZOL-->FSH&LH decrease
-->ENDO-METRIOSIS

4. MENO-TROPIN ~FSH
MENO-PAUSE WOMEN
UR INE
UR oFolin
~CLOMIPHEN USE+
hCG ~ LH

HERMA-PHRODITE

HERMA-PHRODITE:
TRUE=
OVARY+TESTIS
regardless
CHROMOSEMES &
GENITALIA

PSEUDO-HERMAPHR:
1 TYPE GONAD+
OPPOSITE
CHROMOSOM.&
2* SEXUAL CHARACTERISTICS

MALE HERM.=TESTIS
e.g. Testost. rec.defect
W.HERM.=OVARY
e.g. CAH

CHOLESTEROL SYNTHESIS

CHOLESTEROL SYNTHESIS:
Ac.CoA + Ac.CoA=
Ac-ACETYLCoA
4C+
Ac.CoA=
OH-CH3-GLUTARYL-CoA
6C--->
HMG-CoA-RED-ase--->
MEVALONATE=6C--->
/ LONG---> SQUALENE--->
CYCLE---->
LANO-STEROL
4 FUSED RINGS---->

CHOLE-STEROL---->
----> BILE SALTS
--->CS
--->SEX HORMONES
---> Vit. D

ORAL HYPOGLYCEMICS

S-UREA= GLIPIZID
/ S ECRETION b-CELLLS
BI-GUANIDINE
M ETH-FORMINE
M USCLE
/ Glu UPTAKE

APO-LP RECEPTORS

APO-LP RECEPTORS:
A --- HDL
a-ELECTROPHORESIS
B--- LDL
b-LPP
B ED

HEME SYNTHESIS and Porphyria

HEME SYNTHESIS:
KREBS
SUCC.CoA+
AA GLYCINE
AMINO-LEVULINIC
ACID = ALA+
ALA
PORPHO-BIL-GEN+
0 P-B-GENS
URO
COPRO
PROTO
+Fe2+ HEME

REGULATION:
ALA-SYNTHET-ase^-->
A IP

P
P BG/--> URINE
P ORT-WINE
P AIN ABDOMEN-->
P MH-->SURGERY SCARS
P SYCHOSIS

8 ENZYMES
7 DEFFECIVE=
PORHYR-IAS
CI: BARBITURATES

URO-->COPRO ENZ.\-->
PCTarda

Medical Mnemonics