HEME SYNTHESIS and Porphyria

HEME SYNTHESIS:
KREBS
SUCC.CoA+
AA GLYCINE
AMINO-LEVULINIC
ACID = ALA+
ALA
PORPHO-BIL-GEN+
0 P-B-GENS
URO
COPRO
PROTO
+Fe2+ HEME

REGULATION:
ALA-SYNTHET-ase^-->
A IP

P
P BG/--> URINE
P ORT-WINE
P AIN ABDOMEN-->
P MH-->SURGERY SCARS
P SYCHOSIS

8 ENZYMES
7 DEFFECIVE=
PORHYR-IAS
CI: BARBITURATES

URO-->COPRO ENZ.\-->
PCTarda